Lactobacillus plantarum 14D and Reduced Intestinal Ischemia-Reperfusion Injury

• Probiotics improve intestinal ischemia-reperfusion injury: a systematic review and meta-analysis.

  • 2025-05-22
  • Systematic Review · n = 12
  • Frontiers in medicine 12
  • • Zicen Zhao
    • Yuxuan Wu
    • Yufang Leng
    • Liya Chang
    • Yu Wang
    • Dongbin Li
    • Yang Xing

  • PubMed: 40486191
  • DOI: 10.3389/fmed.2025.1546650

  4 Insights on

  • Reduced Intestinal Ischemia-Reperfusion Injury

  • High evidence

  probiotic-added animals had less intestinal damage after IRI compared to controls, as evidenced by a more intact intestinal barrier ... lower Chiu score ... fewer inflammatory factors ... and lower levels of oxidative stress

  Effect

  Beneficial

  Effect size

  Large

  Significant

  Yes