Lactobacillus plantarum 299v and Improved Mitochondrial Function

• Probiotic Lactobacillus plantarum 299v supplementation in patients with major depression in a double-blind, randomized, placebo-controlled trial: A metabolomics study.

  • 2025-01
  • RCT
  • Journal of affective disorders 368
  • • Joanna Godzien
    • Bartlomiej Kalaska
    • Leszek Rudzki
    • Cecilia Barbas-Bernardos
    • Justyna Swieton
    • Angeles Lopez-Gonzalvez
    • Lucyna Ostrowska
    • Agata Szulc
    • Napoleon Waszkiewicz
    • Michal Ciborowski
    • Antonia García
    • Adam Kretowski
    • Coral Barbas
    • Dariusz Pawlak

  • PubMed: 39271063
  • DOI: 10.1016/j.jad.2024.09.058

  3 Insights on

  • Improved Mitochondrial Function

  • High evidence

  Supplementation of SSRI treatment with LP299v intensified the reduction of long-chain acylcarnitines, potentially indicating improved mitochondrial function.

  Effect

  Beneficial

  Effect size

  Small