Probiotic Lactobacillus plantarum 299v supplementation in patients with major depression in a double-blind, randomized, placebo-controlled trial: A metabolomics study.
- 2025-01
- RCT
- Journal of affective disorders 368
- Joanna Godzien
- Bartlomiej Kalaska
- Leszek Rudzki
- Cecilia Barbas-Bernardos
- Justyna Swieton
- Angeles Lopez-Gonzalvez
- Lucyna Ostrowska
- Agata Szulc
- Napoleon Waszkiewicz
- Michal Ciborowski
- Antonia García
- Adam Kretowski
- Coral Barbas
- Dariusz Pawlak
- PubMed: 39271063
- DOI: 10.1016/j.jad.2024.09.058
- High evidence
Supplementation of SSRI treatment with LP299v intensified the reduction of long-chain acylcarnitines, potentially indicating improved mitochondrial function.
- Effect
- Beneficial
- Effect size
- Small