Lactobacillus plantarum 299v and Increased Short-Chain Fatty Acid Production

• Lactobacillus plantarum 299v Enhances the Concentrations of Fecal Short-Chain Fatty Acids in Patients with Recurrent Clostridium difficile-Associated Diarrhea

  • 2007-04-10
  • RCT · n = 19
  • Digestive Diseases and Sciences 52(9)
  • • M. Wullt
    • Marie-Louise Johansson Hagslätt
    • I. Odenholt
    • A. Berggren

  • PubMed: 17420953
  • DOI: 10.1007/s10620-006-9123-3

  4 Insights on

  • Increased Short-Chain Fatty Acid Production

  • High evidence
  • Clinical

  a significant decrease in total short-chain fatty acids was seen in the placebo group (from 77.1 to 45.5 micromol/g; P=0.028) but not in the Lactobacillus group (79.8-60.4 micromol/g)

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes