Probiotic Lactobacillus Plantarum 299v decreases kynurenine concentration and improves cognitive functions in patients with major depression: A double-blind, randomized, placebo controlled study.
- 2019-02
- RCT · n = 40
- Psychoneuroendocrinology 100
- Leszek Rudzki
- Lucyna Ostrowska
- Dariusz Pawlak
- Aleksandra Małus
- Krystyna Pawlak
- Napoleon Waszkiewicz
- Agata Szulc
- PubMed: 30388595
- DOI: 10.1016/j.psyneuen.2018.10.010
- High evidence
- Highly Cited
- Clinical
Repeated Measures ANOVA revealed a significant effect of interaction of Treatment x time for AA concentration. However, results of post hoc analysis did not reach statistical significance in neither probiotic nor placebo group.
- Effect
- Neutral
- Effect size
- Small
- Significant
- No
- Dose
- not specified