Lactobacillus plantarum 299v and Reduced Bacterial Translocation

• A prospective randomised study of the probiotic Lactobacillus plantarum 299V on indices of gut barrier function in elective surgical patients.

  • 2002-12
  • RCT · n = 129
  • Gut 51(6)
  • • C E McNaught
    • N P Woodcock
    • J MacFie
    • C J Mitchell

  • PubMed: 12427785
  • DOI: 10.1136/gut.51.6.827

  3 Insights on

  • Reduced Bacterial Translocation

  • High evidence
  • Large Human Trial
  • Rigorous Journal
  • Clinical

  There was no significant difference between the two groups in terms of bacterial translocation (12% v 12%; p=0.82)

  Effect

  Neutral

  Effect size

  Small

  Significant

  No

• Lactobacillus plantarum 299v does not reduce enteric bacteria or bacterial translocation in patients undergoing colon resection.

  • 2012-03-21
  • RCT
  • Digestive diseases and sciences 57(7)
  • • Peter Mangell
    • Henrik Thorlacius
    • Ingvar Syk
    • Siv Ahrné
    • Göran Molin
    • Crister Olsson
    • Bengt Jeppsson

  • PubMed: 22434095
  • DOI: 10.1007/s10620-012-2102-y

  3 Insights on

  • Reduced Bacterial Translocation

  • High evidence
  • Rigorous Journal
  • Clinical

  Lactobacillus plantarum 299v was established in the intestine, but no inhibitory effect on enteric bacteria, bacterial translocation, or postoperative complications was found.

  Effect

  Neutral

  Effect size

  Small

  Significant

  No