Lactobacillus plantarum 299v and Reduced Postoperative Septic Morbidity

• A prospective randomised study of the probiotic Lactobacillus plantarum 299V on indices of gut barrier function in elective surgical patients.

  • 2002-12
  • RCT · n = 129
  • Gut 51(6)
  • • C E McNaught
    • N P Woodcock
    • J MacFie
    • C J Mitchell

  • PubMed: 12427785
  • DOI: 10.1136/gut.51.6.827

  3 Insights on

  • Reduced Postoperative Septic Morbidity

  • High evidence
  • Large Human Trial
  • Rigorous Journal
  • Clinical

  septic morbidity (13% v 15%; p=0.74)

  Effect

  Neutral

  Effect size

  Small

  Significant

  No