Lactobacillus plantarum DR7 and Reduced Neurodegeneration Symptoms

• Lactobacillus probiotics improved the gut microbiota profile of a Drosophila melanogaster Alzheimer's disease model and alleviated neurodegeneration in the eye.

  • 2020-02-19
  • Clinical Trial
  • Beneficial Microbes 11(1)
  • • F. Tan
    • G. Liu
    • S. A. Lau
    • M. Jaafar
    • Y. Park
    • G. Azzam
    • Y. Li
    • M. Liong

  • PubMed: 32066253
  • DOI: 10.3920/bm2019.0086

  2 Insights on

  • Reduced Neurodegeneration Symptoms

  • Low evidence
  • Animal Study

  The administration of *Lactobacillus* strains was able to rescue the rough eye phenotype (REP) seen in AD-induced *Drosophila*, with a more prominent effect observed upon the administration of *Lactobacillus plantarum* DR7 (DR7).

  Effect

  Beneficial

  Effect size

  Large