Lactobacillus plantarum DR7 and Reduced Nosocomial Infections

• Early and sustained Lactobacillus plantarum probiotic therapy in critical illness: the randomised, placebo-controlled, restoration of gut microflora in critical illness trial (ROCIT)

  • 2021-02-10
  • RCT · n = 218
  • Intensive Care Medicine 47(3)
  • • E. Litton
    • M. Anstey
    • David I. Broadhurst
    • A. Chapman
    • A. Currie
    • J. Ferrier
    • J. Gummer
    • A. Higgins
    • Jolene Lim
    • L. Manning
    • E. Myers
    • Katrina Orr
    • Anne-Marie Palermo
    • A. Paparini
    • S. Pellicano
    • E. Raby
    • A. Rammohan
    • A. Regli
    • Bernhard Richter
    • S. Salman
    • T. Strunk
    • S. Waterson
    • D. Weight
    • B. Wibrow
    • F. Wood

  • PubMed: 33566129
  • DOI: 10.1007/s00134-020-06322-w

  8 Insights on

  • Reduced Nosocomial Infections

  • High evidence
  • Rigorous Journal

  Nosocomial infection occurred in 8 (7.3%) and 5 (4.6%) of the probiotic and placebo group participants, respectively, odds ratio 1.62 (95% CI 0.51-5.10), P = 0.57.

  Effect

  Neutral

  Effect size

  Small

  Significant

  No