Lactobacillus plantarum HA-119 and Improved Oxidative Status

• A Mix of Probiotic Strains Prevents Hepatic Steatosis, and Improves Oxidative Stress Status and Gut Microbiota Composition in Obese Mice.

  • 2024-10-17
  • Molecular nutrition & food research 68(21)
  • • Chenglin Guo
    • Shengduo He
    • Mélanie Le Barz
    • Sylvie Binda
    • Huahong Wang

  • PubMed: 39420712
  • DOI: 10.1002/mnfr.202300672

  2 Insights on

  • Improved Oxidative Status

  • Low evidence
  • Rigorous Journal
  • Animal Study

  The probiotic supplementation significantly downregulates the expression of the proinflammatory cytokines interleukin-1β, tumor necrosis factor-α, and malondialdehyde (MDA) in the liver and upregulated catalase (CAT), superoxide dismutase (SOD), and nuclear respiratory factor 1 (Nrf1) expression.

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes