Lactobacillus plantarum HEAL9 and Reduced Toxicity

• Protective Roles of Prebiotics and Probiotics Against Environmental Pollutant-Induced Toxicities: A Systematic Review of Animal Studies.

  • 2025-09-04
  • Systematic Review
  • Molecular nutrition & food research 70(1)
  • • Meysam Zarezadeh
    • Ahmad Saedisomeolia
    • Mahsa Mahmoudinezhad
    • Michele M Iskandar
    • Fang Lu
    • Stan Kubow

  • PubMed: 40906511
  • DOI: 10.1002/mnfr.70175

  3 Insights on

  • Reduced Toxicity

  • Low evidence
  • Rigorous Journal
  • Animal Study

  Probiotics, prebiotics, synbiotics, and gut microbiota reduced heavy metal absorption and increased fecal excretion. They also improved gut barrier integrity and reduced intestinal permeability in animals exposed to heavy metals. Additionally, probiotics and prebiotics enhanced antioxidant activity and triggered anti-inflammatory responses in animals exposed to heavy metals, mycotoxins, and organic pollutants.

  Effect

  Beneficial

  Effect size

  Moderate