Augmentation of T helper type 1 immune response through intestinal immunity in murine cutaneous herpes simplex virus type 1 infection by probiotic Lactobacillus plantarum strain 06CC2.
- 2016-10
- Clinical Trial
- International Immunopharmacology 39
- Tatsuya Matsusaki
- S. Takeda
- M. Takeshita
- Yuo Arima
- Chuluunbat Tsend-Ayush
- Tsendesuren Oyunsuren
- C. Sugita
- H. Yoshida
- W. Watanabe
- M. Kurokawa
- PubMed: 27517518
- DOI: 10.1016/j.intimp.2016.08.001
- Low evidence
- Rigorous Journal
- Animal Study
oral administration of 06CC2 (20mg/mouse) twice daily for seven days starting two days before infection was significantly effective in delaying the development of skin lesions in the early phase of infection
- Effect
- Beneficial
- Effect size
- Moderate
- Significant
- Yes