Lactobacillus plantarum KABP-061 and Increased Lead Excretion

• Lactobacillus plantarum CCFM8661 modulates bile acid enterohepatic circulation and increases lead excretion in mice.

  • 2019-08-06
  • Clinical Trial
  • Food & Function 10(3)
  • • Q. Zhai
    • Yang Liu
    • Chen Wang
    • DingWu Qu
    • Jianxin Zhao
    • Hao Zhang
    • F. Tian
    • Wei Chen

  • PubMed: 30768114
  • DOI: 10.1039/c8fo02554a

  2 Insights on

  • Increased Lead Excretion

  • Low evidence
  • Animal Study

  L. plantarum CCFM8661 significantly induced hepatic BA synthesis, enhanced bile flow and biliary glutathione output, and increased fecal BA excretion in the mice, which in turn increased biliary Pb output and enhanced fecal Pb excretion.

  Effect

  Beneficial

  Effect size

  Large

  Significant

  Yes