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Evidence-Based Supplement Research
Evidence-Based Supplement Research

Lactobacillus plantarum LP01 and Improved Stool Formation

Research synthesisLow evidenceModerate effect3 studies · 3 beneficial · 0 neutral · 0 harmful

Across 3 studies, all reported beneficial moderate-sized effects of *Lactobacillus plantarum* LP01 on improved stool formation, with statistically significant findings. The evidence primarily comes from large outpatient populations (mean age 55-58 years) with chronic intestinal disorders or undergoing digestive surgery or bowel preparation. Dosing was only reported in one study (1 billion living cells/day), but study durations were not consistently reported.

  • Studied populations: adults with chronic intestinal disorders, adults undergoing digestive surgery, adults undergoing bowel preparation

Caveats: Evidence base is small (only 3 studies) — conclusions should be considered preliminary. Available evidence is overwhelmingly positive — clinical literature in this area is subject to publication bias (null-result studies are less likely to be published or indexed). The supplement was tested in combination with other probiotic strains (Lactobacillus lactis subspecies cremoris LLC02 and Lactobacillus delbrueckii LDD01), so the specific contribution of LP01 alone is unclear.

Generated May 12, 2026
Doses used in studies
  • cells/day: 1 billion (median 1 billion, IQR 1 billion1 billion) 1 study
Safety in these studies
3 of 3 papers
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