Lactobacillus plantarum LP01 and Reduced Gastrointestinal Symptoms

Research synthesisLow evidenceModerate effect3 studies · 3 beneficial · 0 neutral · 0 harmful

Across 3 studies, all reported beneficial effects of Lactobacillus plantarum LP01 on reducing gastrointestinal symptoms, with 2 studies showing statistically significant findings and effect sizes ranging from small to moderate (predominantly moderate). The evidence is drawn from populations undergoing digestive surgery or bowel preparation, with no consistent dose or duration data available.

Studied populations: outpatients undergoing digestive surgery or bowel preparation

Caveats: All studies used LP01 in combination with other probiotic strains (e.g., Lactococcus lactis, Lactobacillus delbrueckii), so the isolated effect of LP01 is not established. The evidence base is limited (3 studies, 2 with moderate quality scores), and no data on dose or duration are available across studies.

Generated May 11, 2026

3 of 3 papers

Post-surgical intestinal dysbiosis: use of an innovative mixture (Lactobacillus plantarum LP01, Lactobacillus lactis subspecies cremoris LLC02, Lactobacillus delbrueckii LDD01).
- 2019-07-10
- Clinical Trial
- Acta bio-medica : Atenei Parmensis 90(7-S)
- - Luigi Bonavina
  - Andrea Arini
  - Leonardo Ficano
  - Donato Iannuzziello
  - Luigi Pasquale
  - Salvo Emanuele Aragona
  - Giorgio Ciprandi
  - Italian Study Group On Digestive Disorders
- PubMed: 31292422
- DOI: 10.23750/abm.v90i7-s.8651
2 Insights on
- Reduced Gastrointestinal Symptoms
- Moderate evidence
Abincol® significantly diminished the presence and the severity of intestinal symptoms
Effect
Beneficial
Effect size
Moderate
Significant
Yes
Is It Advisable to Use Probiotics Routinely After a Colonoscopy? A Rapid Comprehensive Review of the Evidence.
- 2025-06-09
- Review
- Medical sciences (Basel, Switzerland) 13(2)
- - Matteo Piciucchi
  - Alice Rossi
  - Alissa Satriano
  - Raffaele Manta
- PubMed: 40559234
- DOI: 10.3390/medsci13020076
1 Insight on
- Reduced Gastrointestinal Symptoms
- Low evidence
Some studies have positively evaluated the impact of the administration of different mixtures of probiotics in preventing and/or limiting this symptomatology.
Effect
Beneficial
Effect size
Small
Lactobacillus plantarum LP01, Lactobacillus lactis subspecies cremoris LLC02, and Lactobacillus delbrueckii LDD01) in patients undergoing bowel preparation.
- 2019-07-10
- Observational
- Acta bio-medica : Atenei Parmensis 90(7-S)
- - Luigi Bonavina
  - Andrea Ariani
  - Leonardo Ficano
  - Domenico Iannuzziello
  - Luigi Pasquale
  - Salvo Emanuele Aragona
  - Lorenzo Drago
  - Giorgio Ciprandi
  - Italian Study Group On Digestive Disorders
- PubMed: 31292421
- DOI: 10.23750/abm.v90i7-s.8650
2 Insights on
- Reduced Gastrointestinal Symptoms
- Low evidence
Abincol® significantly diminished the presence and the severity of intestinal symptoms
Effect
Beneficial
Effect size
Moderate
Significant
Yes

Lactobacillus plantarum LP01 and Reduced Gastrointestinal Symptoms

Post-surgical intestinal dysbiosis: use of an innovative mixture (Lactobacillus plantarum LP01, Lactobacillus lactis subspecies cremoris LLC02, Lactobacillus delbrueckii LDD01).

Is It Advisable to Use Probiotics Routinely After a Colonoscopy? A Rapid Comprehensive Review of the Evidence.

Lactobacillus plantarum LP01, Lactobacillus lactis subspecies cremoris LLC02, and Lactobacillus delbrueckii LDD01) in patients undergoing bowel preparation.