Probiotics, gut microbiota, and brain health: Exploring therapeutic pathways.
- 2025-07-08
- Review
- AIMS microbiology 11(3)
- Srirengaraj Vijayaram
- Karthikeyan Mahendran
- Hary Razafindralambo
- Einar Ringø
- Suruli Kannan
- Yun-Zhang Sun
- PubMed: 41078543
- DOI: 10.3934/microbiol.2025022
- Low evidence
This study offers novel insights by focusing on psychobiotics, a class of probiotics with targeted neuroactive properties. These microorganisms influence brain function through defined mechanisms, including modulation of neuroinflammation, neurotransmitter production (GABA, serotonin), regulation of the hypothalamic-pituitary-adrenal (HPA) axis, and vagus nerve signaling.
- Effect
- Beneficial
- Effect size
- Small