Microencapsulation and Probiotic Characterization of Lactiplantibacillus plantarum LM-20: Therapeutic Application in a Murine Model of Ulcerative Colitis.
- 2025-02-20
- Nutrients 17(5)
- Cynthia Garfias Noguez
- Morayma Ramírez Damián
- Alicia Ortiz Moreno
- Yazmín Karina Márquez Flores
- Liliana Alamilla Beltrán
- Mario Márquez Lemus
- Luis G Bermúdez Humarán
- María Elena Sánchez Pardo
- PubMed: 40077619
- DOI: 10.3390/nu17050749
- Low evidence
- Rigorous Journal
- Animal Study
mice treated with microencapsulated Lactiplantibacillus plantarum LM-20 showed an 83.3% reduction in the disease activity index (DAI) compared to the ulcerative colitis control group. Moreover, a significant decrease was observed in pro-inflammatory cytokine levels (IL-1β and TNF-α) and myeloperoxidase activity
- Effect
- Beneficial
- Effect size
- Large
- Significant
- Yes