Lactobacillus plantarum and Reduced Immune Cell Activity

• Prebiotics of Lactobacillus plantarum mitigate inflammation but compromise immunity.

  • 2026-04
  • Microbial pathogenesis 213
  • • Shanshan Yang
    • Qiuxia Cao
    • Kexin Yan
    • Zhenkong Cheng
    • Jianhao Zheng
    • Baochao Fan
    • Xu Song
    • Xianyu Bian
    • Gege Zhang
    • Xuesong Yuan
    • Rongli Guo
    • Yuanyuan Wang
    • Hailin Huan
    • Chuping Luo
    • Junshu Yan
    • Bin Li

  • PubMed: 41651082
  • DOI: 10.1016/j.micpath.2026.108363

  2 Insights on

  • Reduced Immune Cell Activity

  • Low evidence
  • Animal Study

  while Lactobacillus plantarum prebiotics alleviate clinical symptoms of inflammation, immune responses involving B cells and DCs are also suppressed, in addition to T cell immune responses.

  Effect

  Harmful

  Effect size

  Moderate