Lactobacillus reuteri ATCC PTA 5289 and Reduced Streptococcus Mutans Levels

• The role of probiotics in preventing dental caries: a systematic review of clinical evidence.

  • 2025-12-02
  • Systematic Review
  • Frontiers in oral health 6
  • • Alessio Danilo Inchingolo
    • Angelo Michele Inchingolo
    • Irene Palumbo
    • Mariafrancesca Guglielmo
    • Lilla Riccaldo
    • Roberta Morolla
    • Francesco Inchingolo
    • Andrea Palermo
    • Gianna Dipalma

  • PubMed: 41409473
  • DOI: 10.3389/froh.2025.1720036

  5 Insights on

  • Reduced Streptococcus Mutans Levels

  • High evidence

  Most clinical trials reported a significant reduction in Streptococcus mutans levels following administration of probiotic strains, particularly Lactobacillus paracasei, Lactobacillus rhamnosus, and Bifidobacterium lactis.

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes