Lactobacillus reuteri ATCC PTA 6475 and Reduced Pathogen Growth

• Inhibitory potential of probiotic strains against pathogens associated with osteomyelitis of the jaws: a quantitative MIC and MBC analysis.

  • 2025-07-06
  • Cellular and molecular biology (Noisy-le-Grand, France) 71(6)
  • • Moayad Baazeem
    • Abdurahman Niazy
    • Sameh Rabea
    • Abdulaziz A Alomiery

  • PubMed: 40618333
  • DOI: 10.14715/cmb/2025.71.6.9

  2 Insights on

  • Reduced Pathogen Growth

  • Low evidence

  Both probiotic strains exhibited significant antibacterial activity against Fusobacterium nucleatum and Actinomyces israelii at low concentrations, achieving MIC of 0.625 µl and MBC of 1.25 µl for both pathogens. In contrast, Staphylococcus aureus demonstrated greater resistance, with MIC and MBC recorded at 100 µl and 200 µl, respectively.

  Effect

  Beneficial

  Effect size

  Moderate