Lactobacillus reuteri DSM 17938 and Magnesium Oxide in Children with Functional Chronic Constipation: A Double-Blind and Randomized Clinical Trial
- 2020-01-15
- RCT · n = 60
- Nutrients 12(1)
- M. Kubota
- Kazuya Ito
- K. Tomimoto
- Mitsuharu Kanazaki
- K. Tsukiyama
- A. Kubota
- H. Kuroki
- M. Fujita
- Y. Vandenplas
- PubMed: 31952280
- DOI: 10.3390/nu12010225
- High evidence
All three groups exhibited significant improvement in defecation frequency in the fourth week compared with the baseline condition (group A: p < 0.05; group B: p < 0.05; group C: p < 0.05).
- Effect
- Beneficial
- Effect size
- Moderate
- Significant
- Yes