Lactobacillus reuteri DSM 17938 and Increased Bowel Movements

• The effectiveness of Lactobacillus reuteri DSM 17938 as an adjunct to macrogol in the treatment of functional constipation in children. A randomized, double-blind, placebo-controlled, multicentre trial.

  • 2018-10
  • RCT · n = 129
  • Clinics and research in hepatology and gastroenterology 42(5)
  • • Agnieszka Wegner
    • Aleksandra Banaszkiewicz
    • Jaroslaw Kierkus
    • Piotr Landowski
    • Anna Korlatowicz-Bilar
    • Sabina Wiecek
    • Jaroslaw Kwiecien
    • Agnieszka Gawronska
    • Lukasz Dembinski
    • Grazyna Czaja-Bulsa
    • Piotr Socha

  • PubMed: 29650440
  • DOI: 10.1016/j.clinre.2018.03.008

  7 Insights on

  • Increased Bowel Movements

  • High evidence
  • Large Human Trial
  • Clinical

  Almost all patients (119/129) increased their bowel movements in both groups (59 vs 60, ns.) and there was no statistically significant difference in the number of bowel movements per week in week 8 between the study and the placebo group (7.5±3.3 vs 6.9±2.5, respectively).

  Effect

  Neutral

  Effect size

  Small

  Significant

  No