The effects of a 6-week intervention with Limosilactobacillus reuteri ATCC PTA 6475 alone and in combination with L. reuteri DSM 17938 on gut barrier function, immune markers, and symptoms in patients with IBS-D-An exploratory RCT.
- 2024-11-01
- RCT
- PloS one 19(11)
- Julia König
- María Fernanda Roca Rubio
- Richard A Forsgård
- Julia Rode
- Jakob Axelsson
- Gianfranco Grompone
- Robert J Brummer
- PubMed: 39485760
- DOI: 10.1371/journal.pone.0312464
- High evidence
- Clinical
The participants in both treatment groups reported less gastrointestinal symptoms after three weeks, but this reached significance only in the dual strain group (total score: p = 0.032)
- Effect
- Beneficial
- Effect size
- Small
- Significant
- Yes