Lactobacillus reuteri DSM 17938 and Reduced Late-Onset Sepsis

• Limosilactobacillus reuteri DSM 17938 as a probiotic in preterm infants: An updated systematic review with meta-analysis and trial sequential analysis.

  • 2023-10-13
  • Meta-Analysis · n = 2,284
  • JPEN. Journal of parenteral and enteral nutrition 47(8)
  • • Ju Li Ang
    • Gayatri Athalye-Jape
    • Shripada Rao
    • Max Bulsara
    • Sanjay Patole

  • PubMed: 37742098
  • DOI: 10.1002/jpen.2564

  4 Insights on

  • Reduced Late-Onset Sepsis

  • High evidence
  • Infants

  Meta-analysis of RCTs showed LR significantly reduced LOS (RR, 0.72 [95% CI, 0.54-0.97]; P = 0.03)

  Effect

  Beneficial

  Effect size

  Small

  Significant

  Yes

• Lactobacillus reuteri DSM 17938 as a Probiotic for Preterm Neonates: A Strain-Specific Systematic Review.

  • 2015-06-09
  • Systematic Review
  • Journal of Parenteral and Enteral Nutrition 40(6)
  • • G. Athalye-Jape
    • Shripada C Rao
    • S. Patole

  • PubMed: 26059900
  • DOI: 10.1177/0148607115588113

  20 Insights on

  • Reduced Late-Onset Sepsis

  • High evidence
  • Clinical

  late-onset sepsis (LOS) (relative risk [RR], 0.66; 95% CI, 0.52 to 0.83; 4 RCTs)

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes