Lactobacillus reuteri DSM 17938 and Reduced Liver Injury

• Lactobacillus reuteri DSM 17938 alleviates d-galactosamine-induced liver failure in rats.

  • 2021-01
  • Clinical Trial
  • Biomedicine & Pharmacotherapy 133
  • • Huiyong Jiang
    • Ren Yan
    • Kaicen Wang
    • Qiangqiang Wang
    • Xiaoxiao Chen
    • Lifeng Chen
    • Lanjuan Li
    • L. Lv

  • PubMed: 33202285
  • DOI: 10.1016/j.biopha.2020.111000

  7 Insights on

  • Reduced Liver Injury

  • Low evidence
  • Rigorous Journal
  • Animal Study

  pretreatment with DSM 17938 not only reduced the elevation in serum alanine aminotransferase, aspartate aminotransferase, gamma-glutamyl transferase, IL-1α, IL-2, IL-18, M-CSF, and MIP-3α levels but also alleviated histological abnormalities of both the terminal ileum and liver induced by d-galactosamine.

  Effect

  Beneficial

  Effect size

  Large