Microenvironment-sensitive hydrogels as promising drug delivery systems for co-encapsulating microbial homeostasis probiotics and anti-inflammatory drugs to treat periodontitis.
- 2025-06
- Review
- Materials today. Bio 32
- Yi Quan
- Huihui Shao
- Nuoya Wang
- Zhonggao Gao
- Mingji Jin
- PubMed: 40230648
- DOI: 10.1016/j.mtbio.2025.101711
- Low evidence
Probiotics, by colonizing the oral cavity, transform the infected site from an environment rich in inflammatory cytokines to a more benign environment, inhibit harmful pathogenic microorganisms, and contribute to overall health.
- Effect
- Beneficial
- Effect size
- Small