Lactobacillus reuteri MAK02L14R and Improved Colic Treatment Effectiveness at Two to Three Weeks

• Evidence of Lactobacillus reuteri to reduce colic in breastfed babies: Systematic review and meta-analysis.

  • 2021-12
  • Meta-Analysis
  • Complementary Therapies in Medicine 63
  • • Angela Pierina Dos Reis Buzzo Zermiani
    • Ana Luiza Pelissari Peçanha de Paula Soares
    • Bárbara Leticia da Silva Guedes de Moura
    • Edson Roberto Arpini Miguel
    • Luciana Dias Ghiraldi Lopes
    • N. Santana
    • T. Da Silva Santos
    • I. G. Demarchi
    • Jorge Juarez Teixeira

  • PubMed: 34627993
  • DOI: 10.1016/j.ctim.2021.102781

  7 Insights on

  • Improved Colic Treatment Effectiveness at Two to Three Weeks

  • High evidence

  There was a significant response in treatment effectiveness (reduction ≥ 50% in average daily crying time) in the first week (p = 0.003). These results were similar in the second, third weeks (p < 0.001 for both outcomes) and fourth weeks (p = 0.002).

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes