Lactobacillus reuteri MAK02L14R and Increased Tolerogenic Dendritic Cells

• Protective effect of Lactobacillus reuteri DSM 17938 against experimental necrotizing enterocolitis is mediated by Toll-like receptor 2.

  • 2018-08-01
  • RCT
  • American Journal of Physiology-Gastrointestinal and Liver Physiology 315(2)
  • • T. Hoang
    • Baokun He
    • Ting Wang
    • D. Tran
    • J. M. Rhoads
    • Yuying Liu

  • PubMed: 29648878
  • DOI: 10.1152/ajpgi.00084.2017

  10 Insights on

  • Increased Tolerogenic Dendritic Cells

  • Low evidence
  • Animal Study

  The percentage of tolerogenic DC in the intestine of WT mice was increased by LR 17938 treatment during NEC, a finding not observed in TLR2-/- mice.

  Effect

  Beneficial

  Effect size

  Moderate