Lactobacillus reuteri MAK02L14R and Increased Treatment Success for Infant Colic

• The Efficacy and Safety of the Probiotic Bacterium Lactobacillus reuteri DSM 17938 for Infantile Colic: A Meta-Analysis of Randomized Controlled Trials

  • 2015-10-28
  • Meta-Analysis
  • PLOS ONE 10(10)
  • • Man Xu
    • Jiao Wang
    • Ning Wang
    • Fei Sun
    • Lin Wang
    • Xiao-hong Liu
    • Vincenzo Lionetti

  • PubMed: 26509502
  • DOI: 10.1371/journal.pone.0141445

  24 Insights on

  • Increased Treatment Success for Infant Colic

  • High evidence
  • Rigorous Journal

  Lactobacillus reuteri increased colic treatment effectiveness at two weeks (RR = 2.84; 95% CI: 1.24-6.50; p = 0.014) and three weeks (relative risk [RR] = 2.33; 95% CI: 1.38-3.93; P = 0.002) but not at four weeks (RR = 1.41; 95% CI: 0.52-3.82; P = 0.498).

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes