Lactobacillus reuteri RC-14 and Reduced Group B Streptococcus Colonization

• Oral Lactobacillus rhamnosus GR-1 and Lactobacillus reuteri RC-14 to reduce Group B Streptococcus colonization in pregnant women: A randomized controlled trial.

  • 2016-08
  • RCT · n = 110
  • Taiwanese Journal of Obstetrics and Gynecology 55(4)
  • • M. Ho
    • Yin-Yi Chang
    • Wei-Chun Chang
    • Hung-Chih Lin
    • Mei-Hung Wang
    • Wu‐Chou Lin
    • T. Chiu

  • PubMed: 27590374
  • DOI: 10.1016/j.tjog.2016.06.003

  1 Insight on

  • Reduced Group B Streptococcus Colonization

  • High evidence
  • Highly Cited
  • Pregnant Women

  The GBS colonization results changed from positive to negative in 21 women in the probiotic group (42.9%) and in nine women in the placebo group (18.0%) during this period (Chi-square p=0.007).

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes

• Effects of oral probiotic supplements on vaginal microbiota during pregnancy: a randomised, double-blind, placebo-controlled trial with microbiome analysis.

  • 2019-04
  • RCT
  • BJOG : an international journal of obstetrics and gynaecology 127(2)
  • • S Husain
    • J Allotey
    • Z Drymoussi
    • M Wilks
    • B M Fernandez-Felix
    • A Whiley
    • J Dodds
    • S Thangaratinam
    • C McCourt
    • E M Prosdocimi
    • W G Wade
    • B M de Tejada
    • J Zamora
    • K Khan
    • M Millar

  • PubMed: 30932317
  • DOI: 10.1111/1471-0528.15675

  3 Insights on

  • Reduced Group B Streptococcus Colonization

  • High evidence
  • Pregnant Women

  There were also no differences between the groups in the proportion of women colonised with the probiotic strains, Escherichia coli, group B streptococci or other vaginal microbiota.

  Effect

  Neutral

  Effect size

  Small

  Significant

  No

  Dose

  2.5 × 10^9 colony-forming units (CFUs) once daily