Lactobacillus reuteri UALre-16 and Improved Stool Consistency

• Lactobacillus reuteri (DSM 17938) in infants with functional chronic constipation: a double-blind, randomized, placebo-controlled study.

  • 2010-10
  • RCT · n = 44
  • The Journal of Pediatrics 157(4)
  • • P. Coccorullo
    • C. Strisciuglio
    • M. Martinelli
    • E. Miele
    • L. Greco
    • A. Staiano

  • PubMed: 20542295
  • DOI: 10.1016/j.jpeds.2010.04.066

  5 Insights on

  • Improved Stool Consistency

  • High evidence
  • Highly Cited

  In the L reuteri group, the stool consistency was reported as hard in 19 infants (86.4%) at baseline, in 11 infants (50%) at week 2, and in 4 infants (18.2%) at weeks 4 and 8. However, there was no significant difference between L reuteri and placebo groups in the stool consistency at all weeks (P=.63, week 2; P=.38, week 4; P=.48, week 8).

  Effect

  Neutral

  Effect size

  Small

  Significant

  No