Lactobacillus reuteri UALre-16 and Induction of Browning of White Adipose Tissue

• Antiobesity effect of Lactobacillus reuteri 263 associated with energy metabolism remodeling of white adipose tissue in high-energy-diet-fed rats.

  • 2018-04
  • The Journal of Nutritional Biochemistry 54
  • • Li-Han Chen
    • Yi-Hsing Chen
    • Kuan-Chen Cheng
    • Ting-Yi Chien
    • Ching‐Hung Chan
    • Shu-Ping Tsao
    • Hui-Yu Huang

  • PubMed: 29329013
  • DOI: 10.1016/j.jnutbio.2017.11.004

  11 Insights on

  • Induction of Browning of White Adipose Tissue

  • Low evidence

  L. reuteri 263 might induce browning of WAT due to the higher mRNA levels of browning-related genes peroxisome proliferator-activated receptor-γ, PR domain containing-16, Pparγ coactivator-1α, bone morphogenetic protein-7 and fibroblast growth factor-21 in the 1X and 5X groups compared to the HE group.

  Effect

  Beneficial

  Effect size

  Large