Lactobacillus reuteri and Improved PAC-QoL Score

• Network meta-analysis of probiotics, prebiotics, and synbiotics for the treatment of chronic constipation in adults.

  • 2024-05-02
  • Systematic Review · n = 903
  • European journal of nutrition 63(6)
  • • Xinxin Deng
    • Cui Liang
    • Liying Zhou
    • Xue Shang
    • Xu Hui
    • Liangying Hou
    • Yongsheng Wang
    • Wendi Liu
    • Shanshan Liang
    • Liang Yao
    • Kehu Yang
    • Xiuxia Li

  • PubMed: 38693449
  • DOI: 10.1007/s00394-024-03410-1

  3 Insights on

  • Improved PAC-QoL Score

  • High evidence
  • Rigorous Journal
  • Clinical

  L. reuteri (MD = -13.74, 95% CI [-22.20, -4.66], very low certainty) exhibited a significant effect in improving the Patient Assessment of Constipation Quality of Life (PAC-QoL) score

  Effect

  Beneficial

  Effect size

  Large

  Significant

  Yes