Skip to main content

Evidence-Based Supplement Research

Evidence-Based Supplement Research

Lactobacillus reuteri and Reduced Pain Attack

Doses used in studies

CFU/day: 100 million (median 100 million, IQR 100 million–100 million) — 1 study

Time to effect

Median: 4.3 weeks · IQR 4.3 weeks–4.3 weeks · Range 4.3 weeks–4.3 weeks — Reported in 1 of 1 study

1 of 1 paper

The impact of probiotics on pulmonary, gastrointestinal, and growth outcomes in pediatric cystic fibrosis: a randomized controlled trial.
- 2025-05-28
- RCT · n = 55
- BMC pediatrics 25(1)
- - Parisa Rahmani
  - Pejman Rohani
  - Arian Kariman
  - Farzaneh Motamed
  - Mohammad Reza Modaresi
  - Kambiz Eftekhari
  - Mehri Ayati
  - Mohammad Hassan Sohouli
- PubMed: 40437397
- DOI: 10.1186/s12887-025-05789-0
6 Insights on
- Reduced Pain Attack
- High evidence
- Clinical
The only notable effect reported was related to pain attacks in the probiotic group compared to the placebo group after 4 weeks (P = 0.02).
Effect
Beneficial
Effect size
Small
Significant
Yes
Dose
10^8 CFU/d