Effect of adjuvant probiotic therapy (Lactobacillus reuteri) in the treatment of periodontitis associated with diabetes mellitus: clinical, controlled, and randomized study.
- 2024-01-06
- RCT · n = 20
- Clinical oral investigations 28(1)
- Maria Aparecida Neves Jardini
- Juliana Fatima Pedroso
- Camila Lopes Ferreira
- Camilla Magnoni Moretto Nunes
- Cadiele Oliana Reichert
- Marlene Nunez Aldin
- Antonio Martins Figueiredo Neto
- Debora Levy
- Nagila Raquel Teixeira Damasceno
- PubMed: 38183505
- DOI: 10.1007/s00784-023-05441-0
- High evidence
- Clinical
For the PISA, SI + Probi showed a significant difference (p = 0.04) compared to SI + Placebo at 90 days.
- Effect
- Harmful
- Effect size
- Small
- Significant
- Yes
- Dose
- not specified