Lactobacillus rhamnosus DSM 6594 and Improved Gut Barrier Function

• Effectiveness of Probiotics and Prebiotics Against Acute Liver Injury: A Meta-Analysis.

  • 2021-09-21
  • Systematic Review
  • Frontiers in medicine 8
  • • Sheng Xu
    • Min Zhao
    • Qinjian Wang
    • Zhihua Xu
    • Binhui Pan
    • Yilang Xue
    • Zebin Dai
    • Sisi Wang
    • Zhanxiong Xue
    • Fangyan Wang
    • Changlong Xu

  • PubMed: 34621765
  • DOI: 10.3389/fmed.2021.739337

  4 Insights on

  • Improved Gut Barrier Function

  • High evidence

  Tight junction protein ZO-1 (SMD: 1.95, 95% CI: 0.14 to 3.76) was upregulated after intervention, thereby reducing bacterial translocation to the liver [odds ratio (OR) = 0.23, 95% CI: 0.13-0.44] and mesenteric lymph node (OR = 0.14, 95% CI: 0.08 to 0.26)

  Effect

  Beneficial

  Effect size

  Large

  Significant

  Yes