Lactobacillus rhamnosus DSM33560 and Reduced Clinically Relevant Anxiety

• Effect of Lactobacillus rhamnosus HN001 in Pregnancy on Postpartum Symptoms of Depression and Anxiety: A Randomised Double-blind Placebo-controlled Trial

  • 2017-10
  • RCT · n = 423
  • EBioMedicine 24
  • • R. Slykerman
    • Fiona Hood
    • K. Wickens
    • John F. Thompson
    • C. Barthow
    • R. Murphy
    • Janice Kang
    • Judy Rowden
    • P. Stone
    • Julian Crane
    • T. Stanley
    • P. Abels
    • G. Purdie
    • Robyn M. Maude
    • E. Mitchell

  • PubMed: 28943228
  • DOI: 10.1016/j.ebiom.2017.09.013

  6 Insights on

  • Reduced Clinically Relevant Anxiety

  • High evidence
  • Large Human Trial
  • Highly Cited
  • Rigorous Journal
  • Pregnant Women

  Rates of clinically relevant anxiety on screening (score>15) were significantly lower in the HN001 treated mothers (OR=0·44 (0·26, 0·73), p=0·002).

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes