Lactobacillus rhamnosus GR-1 and Reduced Preterm Births

• Probiotic Lactobacillus rhamnosus GR-1 is a unique prophylactic agent that suppresses infection-induced myometrial cell responses.

  • 2019-03-18
  • Scientific reports 9(1)
  • • Bona Kim
    • Oksana Shynlova
    • Stephen Lye

  • PubMed: 30886179
  • DOI: 10.1038/s41598-019-41133-0

  2 Insights on

  • Reduced Preterm Births

  • Low evidence
  • Rigorous Journal

  In pregnant mice, prophylactic administration of probiotic Lactobacillus rhamnosus GR-1 supernatant (GR1SN) prevented lipopolysaccharide (LPS)-induced PTB and reduced cytokine expression in the uterine muscle (myometrium).

  Effect

  Beneficial

  Effect size

  Moderate