Lactobacillus rhamnosus HA-500 and Reduced Cytotoxicity

• Postbiotic_Loaded Hyalurosome: Investigating Their Potential as Antimicrobial and Antioxidant Agents.

  • 2026-04
  • Journal of cosmetic dermatology 25(4)
  • • Seyede Fateme Morakabi
    • Mahvash Khodabandeh Shahraky
    • Gholamreza Ahmadian
    • Roghayeh Mokhtari Asl

  • PubMed: 41999161
  • DOI: 10.1111/jocd.70777

  2 Insights on

  • Reduced Cytotoxicity

  • Low evidence

  Encapsulation significantly reduced cytotoxicity, increasing human dermal fibroblast viability from 60% (free CFS) to over 90% at a 6.25% (v/v) concentration.

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes