Lactobacillus rhamnosus HA-500 and Reduced Periodontal Inflammation

• Dual-functional probiotic hydrogel with puerarin integration for microbiota-neuroimmune regulation in antibiotic-free periodontitis therapy.

  • 2025-11
  • Bioactive materials 53
  • • Yi Wang
    • Yansheng Qu
    • Xiangmei Liu
    • Jin Huang
    • Congyang Mao
    • Chaofeng Wang
    • Shengli Zhu
    • Yufeng Zheng
    • Zhaoyang Li
    • Zhenduo Cui
    • Hui Jiang
    • Yang Lv
    • Jie Shen
    • Shuilin Wu

  • PubMed: 40688024
  • DOI: 10.1016/j.bioactmat.2025.07.004

  2 Insights on

  • Reduced Periodontal Inflammation

  • Low evidence

  This study provides a potential strategy for the antibiotic-free treatment of periodontitis...

  Effect

  Beneficial

  Effect size

  Moderate