Effect of early probiotic supplementation on childhood cognition, behaviour and mood a randomised, placebo-controlled trial.
- 2018-10-22
- RCT · n = 474
- Acta paediatrica (Oslo, Norway : 1992) 107(12)
- R F Slykerman
- J Kang
- N Van Zyl
- C Barthow
- K Wickens
- T Stanley
- C Coomarasamy
- G Purdie
- R Murphy
- J Crane
- E A Mitchell
- PubMed: 30246890
- DOI: 10.1111/apa.14590
- High evidence
- Large Human Trial
- Children
Overall, there were no significant differences in the neurocognitive outcomes between the treatment groups.
- Effect
- Neutral
- Effect size
- Small
- Significant
- No
- Dose
- daily from 35 weeks gestation until six months if breastfeeding, and the same treatment from birth to two years