Lactobacillus rhamnosus HN001 and Improved Gut Barrier Function

• The therapeutic effects of Lacticaseibacillus rhamnosus on stress-induced anxiety: a systematic review of evidence from animal studies.

  • 2026-01-07
  • Review · n = 8
  • Gut microbiome (Cambridge, England) 6
  • • Iman Imtiyaz Ahmed Juvale
    • Alina Arulsamy

  • PubMed: 41497537
  • DOI: 10.1017/gmb.2025.10015

  6 Insights on

  • Improved Gut Barrier Function

  • Low evidence

  Mechanistic findings were reported in subsets of studies: tight junction restoration in 2/15

  Effect

  Beneficial

  Effect size

  Small

• Probiotics Attenuate Food Allergy via Short-Chain Fatty Acids-Mediated Immune Modulation and Gut Barrier Restoration.

  • 2025-11-18
  • Foods (Basel, Switzerland) 14(22)
  • • Xue Feng
    • Liuying Li
    • Li Yan
    • Zhencong Yan
    • Zhoujin Xu
    • Yuting Fan
    • Philippe Madjirebaye
    • Xuli Wu

  • PubMed: 41300111
  • DOI: 10.3390/foods14223953

  5 Insights on

  • Improved Gut Barrier Function

  • Low evidence

  Treatment also restored intestinal integrity by upregulating tight junction proteins (ZO-1, claudin-1).

  Effect

  Beneficial

  Effect size

  Moderate