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Evidence-Based Supplement Research

Evidence-Based Supplement Research

Lactobacillus rhamnosus HN001 and Increased Interferon-Gamma Levels

Doses used in studies

CFU/day: 75 million (median 75 million, IQR 75 million–75 million) — 1 study

Time to effect

Median: 8 weeks · IQR 8 weeks–8 weeks · Range 8 weeks–8 weeks — Reported in 1 of 1 study

1 of 1 paper

Effect of synbiotic supplementation on immune parameters and gut microbiota in healthy adults: a double-blind randomized controlled trial.
- 2023-08-23
- RCT
- Gut microbes 15(2)
- - Xiaoqin Li
  - Shan Hu
  - Jiawei Yin
  - Xiaobo Peng
  - Lei King
  - Linyan Li
  - Zihui Xu
  - Li Zhou
  - Zhao Peng
  - Xiaolei Ze
  - Xuguang Zhang
  - Qiangchuan Hou
  - Zhilei Shan
  - Liegang Liu
- PubMed: 37614109
- DOI: 10.1080/19490976.2023.2247025
4 Insights on
- Increased Interferon-Gamma Levels
- High evidence
- Adults
Compared to the placebo group, participants receiving synbiotic supplementation exhibited greater reductions in plasma ... interferon-gamma (P=0.008)
Effect
Beneficial
Effect size
Small
Significant
Yes
Dose
7.5×10^7 CFU/d