Lactobacillus rhamnosus HN001 and Prolonged Cardiac Allograft Survival

• Lactobacillus rhamnosus HN001 facilitates the efficacy of dual PI3K/mTOR inhibition prolonging cardiac transplant survival and enhancing antitumor effect.

  • 2024-05-02
  • Microbiology spectrum 12(5)
  • • Xiaolong Miao
    • Peng Jiang
    • Xiaotong Zhang
    • Xinqiang Li
    • Zelai Wu
    • Yuancong Jiang
    • Han Liu
    • Weixun Xie
    • Xinwei Li
    • Bingfeng Shi
    • Jinzhen Cai
    • Weihua Gong

  • PubMed: 38564670
  • DOI: 10.1128/spectrum.01839-23

  4 Insights on

  • Prolonged Cardiac Allograft Survival

  • Low evidence
  • Animal Study

  the combination of BEZ235 and Lactobacillus rhamnosus HN001 significantly prolonged cardiac transplant survival

  Effect

  Beneficial

  Effect size

  Large

  Significant

  Yes