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Evidence-Based Supplement Research

Evidence-Based Supplement Research

Lactobacillus rhamnosus HN001 and Reduced Fasting Glucose

Doses used in studies

sachet/day: 1 (median 1, IQR 1–1) — 1 study

Time to effect

Median: 4 months · IQR 4 months–4 months · Range 4 months–4 months — Reported in 1 of 2 studies

2 of 2 papersPopulation:

Effect of Lactobacillus rhamnosus Probiotic in Early Pregnancy on Plasma Conjugated Bile Acids in a Randomised Controlled Trial
- 2021-01-13
- RCT · n = 348
- Nutrients 13(1)
- - Yutao Chen
  - Jun Lu
  - K. Wickens
  - T. Stanley
  - Robyn M. Maude
  - P. Stone
  - C. Barthow
  - J. Crane
  - E. Mitchell
  - F. Merien
  - R. Murphy
- PubMed: 33450885
- DOI: 10.3390/nu13010209
7 Insights on
- Reduced Fasting Glucose
- High evidence
- Large Human Trial
Women supplemented with HN001 had lower fasting glucose compared with placebo (p = 0.040)
Effect
Beneficial
Effect size
Small
Significant
Yes
Gut microbiota composition after diet and probiotics in overweight breast cancer survivors: a randomized open-label pilot intervention trial.
- 2020-06
- RCT · n = 34
- Nutrition (Burbank, Los Angeles County, Calif.) 74
- - Marianna Pellegrini
  - Mirko Ippolito
  - Taira Monge
  - Rossella Violi
  - Paola Cappello
  - Ilario Ferrocino
  - Luca Simone Cocolin
  - Antonella De Francesco
  - Simona Bo
  - Concetta Finocchiaro
- PubMed: 32234652
- DOI: 10.1016/j.nut.2020.110749
10 Insights on
- Reduced Fasting Glucose
- High evidence
- Clinical
Significant reductions of body weight, body mass index, fasting glucose, and homeostasis model assessment of insulin resistance were identified at T4 in both groups; ... in the intervention group ...
Effect
Neutral
Effect size
Small
Significant
No
Dose
1 sachet/d