Evidence-based mixture containing Lactobacillus strains and lactoferrin to prevent recurrent bacterial vaginosis: a double blind, placebo controlled, randomised clinical trial.
- 2019-02-08
- RCT
- Beneficial microbes 10(1)
- R Russo
- E Karadja
- F De Seta
- PubMed: 30525953
- DOI: 10.3920/bm2018.0075
- High evidence
- Rigorous Journal
- Clinical
The results showed that symptoms (vaginal discharge and itching), Nugent score and recurrence rate were significantly improved by probiotics mixture in association with lactoferrin.
- Effect
- Beneficial
- Effect size
- Small
- Significant
- Yes
- Dose
- 2 capsules/day for 5 days followed by 1 capsule/day for 10 consecutive days (induction phase); then 1 capsule/day for 10 consecutive days each month (maintenance phase)