Lactobacillus rhamnosus HN001 and Reduced Staphylococcus aureus Carriage

• Effect of Lactobacillus rhamnosus HN001 on carriage of Staphylococcus aureus: results of the impact of probiotics for reducing infections in veterans (IMPROVE) study

  • 2018-03-14
  • RCT · n = 113
  • BMC Infectious Diseases 18(1)
  • • S. Eggers
    • A. Barker
    • S. Valentine
    • T. Hess
    • M. Duster
    • N. Safdar

  • PubMed: 29540160
  • DOI: 10.1186/s12879-018-3028-6

  2 Insights on

  • Reduced Staphylococcus aureus Carriage

  • High evidence
  • Rigorous Journal

  Those in the probiotic group compared to the placebo group had 73% reduced odds (OR 0.27, 95% CI 0.07-0.98) of methicillin-susceptible S. aureus presence, and 83% reduced odds (OR 0.17, 95% CI 0.04-0.73) of any S. aureus presence in the stool sample at endpoint.

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes