Probiotics Lactobacillus acidophilus LA4 and Lacticaseibacillus paracasei F5 Alleviate Cognitive Dysfunction in Alzheimer's Disease Models: A Dual-Screening Study in Drosophila and Mice.
- 2026-01-24
- Foods (Basel, Switzerland) 15(3)
- Jia Liu
- Guoqing Ren
- Siyi Niu
- Yongshuai Liu
- Yuqing Zhao
- Zhenou Sun
- Qiaomei Zhu
- Jixiang Zhang
- Yufeng Mao
- Zhengqi Liu
- Qingbin Guo
- Huanhuan Liu
- PubMed: 41683016
- DOI: 10.3390/foods15030429
- Low evidence
LA4 and F5 significantly ameliorated cognitive deficits and anxiety-like behaviors... Consequently, LA4 and F5 alleviate AD pathology by restructuring microbial and metabolic profiles, thereby mitigating neuroinflammation and oxidative stress.
- Effect
- Beneficial
- Effect size
- Large
- Significant
- Yes