Association between probiotic intervention and sleep quality in the general adult population: a systematic review and meta-analysis.
- 2026-03-25
- Systematic Review · n = 890
- Frontiers in nutrition 13
- Tingjing Ren
- Yilin Wang
- Bingnan Zhang
- Haiyan Du
- Huixia Ren
- Naijin Zhang
- Hongwu Wang
- Yuanyuan Guan
- PubMed: 41958906
- DOI: 10.3389/fnut.2026.1795450
- High evidence
Probiotic supplementation significantly reduced PSQI scores compared to the control group (mean difference [MD] = -0.59, 95% confidence interval [CI]: -0.83 to -0.35, p < 0.001) ... For the Insomnia Severity Index (ISI), the probiotic group also showed significantly lower scores (MD = -0.86, 95% CI: -1.60 to -0.12, p = 0.02).
- Effect
- Beneficial
- Effect size
- Small
- Significant
- Yes