Lactobacillus rhamnosus LRa05 and Increased Short-Chain Fatty Acid Production

• Multi-Strain Probiotics BLa80, LRa05, and BBr60 Modulate Inflammation, Bile Acids, and Gut Microbiota in Type 2 Diabetes: A Randomized Controlled Trial.

  • 2026-04
  • RCT · n = 80
  • Food science & nutrition 14(4)
  • • Sijia Zhu
    • Yan Qiao
    • Wenjing He
    • Yaojie Xiao
    • Guiqin Song
    • Kang Liu
    • Shuguang Fang

  • PubMed: 41971606
  • DOI: 10.1002/fsn3.71735

  4 Insights on

  • Increased Short-Chain Fatty Acid Production

  • High evidence

  SCFA analysis showed higher isobutyric and isovaleric acid after supplementation.

  Effect

  Beneficial

  Effect size

  Small

• Lactobacillus rhamnosus LRa05 Alleviates Constipation via Triaxial Modulation of Gut Motility, Microbiota Dynamics, and SCFA Metabolism.

  • 2025-06-28
  • Foods (Basel, Switzerland) 14(13)
  • • Jingxin Zhang
    • Qian Li
    • Shanshan Liu
    • Ning Wang
    • Yu Song
    • Tao Wu
    • Min Zhang

  • PubMed: 40647045
  • DOI: 10.3390/foods14132293

  4 Insights on

  • Increased Short-Chain Fatty Acid Production

  • Low evidence

  Thus, LRa05 could boost short chain fatty acid (SCFA) production, which is vital for stimulating intestinal motility, improving mucosal function, and relieving constipation.

  Effect

  Beneficial

  Effect size

  Moderate