Lactobacillus rhamnosus GG Attenuates Lipopolysaccharide-Induced Inflammation and Barrier Dysfunction by Regulating MAPK/NF-κB Signaling and Modulating Metabolome in the Piglet Intestine.
- 2020-05
- RCT · n = 6
- The Journal of Nutrition 150(5)
- Jiangdi Mao
- Siri Qi
- Yanjun Cui
- Xiaoxiao Dou
- Xin M. Luo
- Jianxin Liu
- T. Zhu
- Yanfei Ma
- Haifeng Wang
- PubMed: 32027752
- DOI: 10.1093/jn/nxaa009
- Low evidence
- Animal Study
The concentrations of caprylic acid [fold-change (FC) = 2.39], 1-mono-olein (FC = 2.68), erythritol (FC = 4.62), and ethanolamine (FC = 4.47) significantly increased in the intestine of LGG + LPS piglets compared with the LPS group.
- Effect
- Beneficial
- Effect size
- Moderate
- Significant
- Yes